Before the COVID-19 era, for ages in medicine it has been said: “Syphilis is often referred to as “the great masquerader,” as it may present with a wide array of clinical symptoms and may mimic a variety of other diseases making diagnosis challenging.” There is no doubt that COVID-19 vaccine injury syndromes will far eclipse syphilis, sarcoidosis, amyloidosis, or any other systemic disorder and will assume the throne of “the great masquerader”. In a recent issue of Current Neurology and Neuroscience Reports, Chatterjee and Chakravarty, report on the wide range of central nervous system and peripheral nervous system syndromes that occur after COVID-19 vaccination.

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