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Health/Medical
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Title: Survey: Pain patients overwhelmingly prefer medical marijuana over opioids
Source: ArsTechnica
URL Source: https://arstechnica.com/science/201 ... edical-marijuana-over-opioids/
Published: Jun 29, 2017
Author: Beth Mole
Post Date: 2017-06-29 12:14:32 by Tooconservative
Keywords: None
Views: 11692
Comments: 46

Of those who used both opioids and cannabis, 92% say they prefer the latter.

When patients have a choice between opioids and medical marijuana for a painful condition, an overwhelming majority say they prefer marijuana, that it works just as well, and has fewer side effects, a new survey finds.

Though the survey, involving 2,897 medical cannabis patients, didn’t track actual drug use or efficacy, the findings fits with previous data. Decades of research suggest marijuana is effective for pain treatment. And recent studies have found that in states with medical marijuana availability, there are fewer opioid overdose deaths and doctors fill fewer opioid prescriptions.

The authors of the new survey, led by Amanda Reiman of the University of California, Berkeley, say the data furthers the need to examine marijuana as a “viable substitute for pain treatment,” particularly in light of the devastating opioid epidemic now gripping the country. The Centers for Disease Control and Prevention reports that opioids killed more than 33,000 Americans in 2015, and estimates that 91 people in the US die each day from the highly addictive drugs.

Though people using marijuana can develop use disorders, it is virtually impossible to die of an overdose—no marijuana overdose deaths have ever been reported to the Drug Enforcement Administration.

“A society with less opioid dependent people will result in fewer public health harms,” the authors of the new study note.

For their survey, the researchers partnered with (but were not paid by) HelloMD, an online community for medical cannabis patients. Of the 2,897 patients recruited for the survey, 63 percent were using marijuana for pain-related conditions, such as fibromyalgia, back pain, and arthritis. About 30 percent, or 841 patients, also reported using an opioid currently or in the past six months.

Of those 841, 92 percent agreed or strongly agreed with the statement that they preferred cannabis over opioids for their condition. And 93 percent agreed or strongly agreed that they were more likely to pick cannabis over opioids if both were readily available. Most also said that cannabis was just as effective at relieving pain as opioids, with 71 percent agreeing or strongly agreeing with the statement. Last, 97 percent agreed or strongly agreed that they could cut down on opioid use if cannabis is available.

The researchers found similar results when they asked about non-opioid pain medication use (see data above).

The survey has limitations. It’s pulling from a self-selected group of cannabis users, for one, so they may be biased. The survey data also doesn’t include actual drug use data or efficacy, just perceptions, which may be skewed.

Researchers need more data to make firm conclusions. But with the data available, the authors suggest that “providing the patient with the option of cannabis as a method of pain treatment alongside the option of opioids might assist with pain relief in a safer environment with less risk.”

Cannabis and Cannabinoid Research, 2017. DOI: 10.1089/can.2017.0012  (About DOIs).


Poster Comment:

A few spiffy charts at Ars if you click over there.(1 image)

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Begin Trace Mode for Comment # 23.

#1. To: Tooconservative (#0)

The survey was administered through e-mail to a database of 67,422 medical cannabis patients in the state of California using the HelloMD patient database. 2897 responded.

Opioids are the strongest medication for pain available. Marijuana has the pain relief of Tylenol. To compare the two is ludicrous.

E-mailing a survey to marijuana users and asking them about the efficacy of marijuana is like e-mailing a survey only to Lexus users and asking them what kind of car they prefer.

What a joke.

misterwhite  posted on  2017-06-29   12:33:31 ET  Reply   Untrace   Trace   Private Reply  


#3. To: misterwhite, Pinguinite (#1)

Opioids are the strongest medication for pain available. Marijuana has the pain relief of Tylenol. To compare the two is ludicrous.

THC is pretty worthless for pain relief, either sativa or indica.

CBD, however, has a pretty strong body effect. CBD is not the usual pot high. Recreational pot is high in various types of THC and related compounds (cannabinoids).

I don't find it hard to believe that opioid users find it easier to quit if they're using a CBD extract. CBD does have an effect but you wouldn't call it "stoned" or even "high".

Tooconservative  posted on  2017-06-29   13:50:13 ET  Reply   Untrace   Trace   Private Reply  


#4. To: Tooconservative (#3)

If you're in the kind of pain where you need opioids to neutralize it, marijuana is not even on the radar. On the other hand, if marijuana treats what little "pain" you have you should not be taking opioids.

misterwhite  posted on  2017-06-29   13:57:08 ET  Reply   Untrace   Trace   Private Reply  


#5. To: misterwhite (#4)

I'm sure that all sounds good to you, typing away on your keyboard.

But in the real world, people are addicted to opioids with many turning to street drugs if their scripts get cut off (in the ongoing Great Opioid Crackdown).

There is no comparison of the reduction in harm if someone is using CBD and staying off opioids. Or just reducing their opioid use considerably.

Tooconservative  posted on  2017-06-29   14:08:51 ET  Reply   Untrace   Trace   Private Reply  


#9. To: Tooconservative (#5)

But in the real world, people are addicted to opioids with many turning to street drugs if their scripts get cut off (in the ongoing Great Opioid Crackdown).

We're on the same page. And I agree that if an opioid addict can't get his fix, marijuana is better than nothing.

All I'm saying is that there's no comparison between the two drugs. Not the "high". Not the medical value. This article is simply a propaganda piece.

misterwhite  posted on  2017-06-29   14:30:13 ET  Reply   Untrace   Trace   Private Reply  


#11. To: misterwhite (#9)

We're on the same page. And I agree that if an opioid addict can't get his fix, marijuana is better than nothing.

I think it might help people kick or at least reduce their opioid habit. If so, we do have an opioid crisis in this country.

Keep in mind: the hippies were always after the THC. No hippie ever wanted a CBD "high" because it's too mild. The medical marijuana people are almost exclusively interested in the CBD and try constantly to reduce the amount of THC that ends up in their CBD products. Most of them try to get down to around 2% THC in their CBD products.

Whether THC is ever accepted medically is an open question. I think the various forms of CBD will eventually be recognized medically as being as useful as aspirin against a variety of ailments, just as they are today for stimulating appetite for cancer patients, treating glaucoma and severe epilepsy.

I think we'll see that in 5-10 years, possibly a little sooner.

Tooconservative  posted on  2017-06-29   14:57:49 ET  Reply   Untrace   Trace   Private Reply  


#16. To: Tooconservative (#11)

Whether THC is ever accepted medically is an open question.

It was the first cannabinoid to be accepted medically (Marinol).

misterwhite  posted on  2017-06-29   17:52:50 ET  Reply   Untrace   Trace   Private Reply  


#19. To: misterwhite, Tooconservative (#16)

Whether THC is ever accepted medically is an open question.

It was the first cannabinoid to be accepted medically (Marinol).

The approval is a bit more nuanced than a legalization of THC, which remains on Schedule I. Marinol has been downgraded to Schedule III.

Schedules of Controlled Substances: Rescheduling of the Food and Drug Administration Approved Product Containing Synthetic Dronabinol [(-)-greek-D SUP9/SUP-(trans)-Tetrahydrocannabinol] in Sesame Oil and Encapsulated in Soft Gelatin Capsules From Schedule II to Schedule III

A Rule by the Drug Enforcement Administration on 07/02/1999

[PDF] https://www.gpo.gov/fdsys/pkg/FR-1999-07-02/pdf/99-16833.pdf

[TEXT] https://www.gpo.gov/fdsys/pkg/FR-1999-07-02/html/99-16833.htm

SUMMARY: This is a final rule of the Deputy Administrator of the Drug Enforcement Administration (DEA) transferring a drug between schedules of the Controlled Substances Act (CSA) pursuant to 21 U.S.C. 811. With the issuance of this final rule, the Deputy Administrator transfers from schedule II to schedule III of the CSA the drug containing synthetic dronabinol [(-)- 9-(trans)- tetrahydrocannabinol] in sesame oil and encapsulated in soft gelatin capsules in a product approved by the Food and Drug Administration (FDA). This rule also designates this drug as a schedule III non- narcotic substance requiring an import/export permit. As a result of this rule, the regulatory controls and criminal sanctions of schedule III will be applicable to the manufacture, distribution, importation and exportation of this drug.

EFFECTIVE DATE: July 2, 1999.

- - - - - - - - - - - - - - - - - - - -

SUPPLEMENTARY INFORMATION:

Background

Dronabinol is the United States Adopted Name (USAN) for the (-)- isomer of 9-(trans)-tetrahydrocannabinol [(-)- 9-(trans)-THC], which is believed to be the major psychoactive component of Cannibas sativa L. (marijuana). On May 31, 1985, FDA approved for marketing the product Marinol --which contains synthetic dronabinol in sesame oil and encapsulated in soft gelatin capsules--for the treatment of nausea and vomiting associated with cancer chemotherapy. Following this FDA approval, DEA issued a final rule on May 13, 1986, transferring FDA-approved products of the same formulation as Marinol from schedule I to schedule II of the CSA in accordance with 21 U.S.C. 811(a). (For simplicity within this document, the term "Marinol'' will be used hereafter to refer to Marinol and any other products, which may by approved by FDA in the future, that have the same formulation as Marinol.) The 1986 rescheduling of Marinol was based on a medical and scientific evaluation and scheduling recommendation from the Assistant Secretary for Health in accordance with 21 U.S.C. 811(b). The transfer of Marinol to schedule II did not affect the CSA classification of pure dronabinol, which--as a tetrahydrocannabinol with no currently accepted medical use in treatment in the United States--remains a schedule I controlled substance. On December 22, 1992, FDA expanded Marinol 's indications to include the treatment of anorexia associated with weight loss in patients with AIDS.

nolu chan  posted on  2017-06-29   19:24:14 ET  Reply   Untrace   Trace   Private Reply  


#20. To: nolu chan (#19)

On May 31, 1985, FDA approved for marketing the product Marinol...

No one cares about Marinol because it just is not effective. It never was.

It's been 15-20 years since I recall anyone even mentioning this fake drug.

Tooconservative  posted on  2017-06-29   19:49:25 ET  Reply   Untrace   Trace   Private Reply  


#23. To: Tooconservative (#20)

"No one cares about Marinol because it just is not effective. It never was."

So you expect pharmaceuticals to spend tens of millions of dollars to research marijuana to find the next cannabinoid with medical value so dopers can then claim that "marijuana is medicine" and smoke dope instead of purchasing the drug from the pharmaceutical company?

And you wonder why there's no marijuana research being done.

misterwhite  posted on  2017-06-30   9:34:03 ET  Reply   Untrace   Trace   Private Reply  


Replies to Comment # 23.

#24. To: misterwhite (#23)

So you expect pharmaceuticals to spend tens of millions of dollars to

I said no such thing. You're hallucinating.

Tooconservative  posted on  2017-06-30 09:42:04 ET  Reply   Untrace   Trace   Private Reply  


#40. To: misterwhite, Tooconservative (#23)

And you wonder why there's no marijuana research being done.

There is little or no research on inhaled marijuana because it is in apparent impossibility to meet required standards for all medicines.

81 Fed Reg No 156 (12 Aug 2016) 53767-53845, Proposed Rules Denial, Docket DEA-427

"Marijuana has no currently accepted medical use in treatment in the United States. Based on the established five-part test for making such determination, marijuana has no "currently accepted medical use" because: As detailed in the HHS evaluation, the drug’s chemistry is not known and reproducible...."

The impossible task is producing a marijuana cigarette which, upon smoking and inhalation, provides a specific yield of a known and reproducible chemical stew.

The specific delivery system of inhaled smoke makes it daunting or impossible to prescribe a known, predictable dose of the active ingredient. To meet medical standards, the rest of the accompanying chemical stew must also be known and predictable and safe.

nolu chan  posted on  2017-06-30 16:35:42 ET  Reply   Untrace   Trace   Private Reply  


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