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Title: Elizabeth Edwards: Patients' 'Gut-Wrenching' Decisions to End Treatment
Source: ABC News
URL Source: http://abcnews.go.com/Health/elizab ... ry?id=12332518&tqkw=&tqshow=WN
Published: Dec 7, 2010
Author: KIM CAROLLO
Post Date: 2010-12-07 14:30:10 by WhiteSands
Keywords: Elizabeth Edwards, Cancer
Views: 1332
Comments: 4

Between September and the end of November, Elizabeth Edwards' health went into a rapid decline. Her breast cancer spread to her liver, and has now reached the point where medical treatment can no longer do much for her.

Although she appeared well enough to make public appearances just a few months ago, medical experts who are not involved with Edwards' treatment say it's not unusual for metastatic breast cancer to quickly progress into its final stages.

"Once the last of all of the likely therapies stops working, it is typical for deterioration to be quite rapid," said Dr. Harry D. Bear, professor of oncology at Virginia Commonwealth University in Richmond, Va.

Edwards' cancer is reportedly the estrogen receptor-positive (ER-positive) type, meaning the cancer grows in high-estrogen environments. Doctors say it's the most common form of breast cancer, and is also the type that leads to the most deaths.

"The majority of breast cancer patients die from ER-positive cancer that's become resistant to anti- hormone drugs than any type of cancer," said Dr. Matthew Ellis, professor of medicine at Washington University School of Medicine in St. Louis, Mo. "The cancer relapses despite the use of these drugs."

Decision to End Treatment "Gut-Wrenching"

Medical experts say how long to continue therapy for metastatic breast cancer, which will eventually become resistant to therapy, is a difficult decision. It requires balancing the effectiveness of treatment and a patient's quality of life.

"The decision when to stop chemotherapy and focus on symptom management is one of the most gut-wrenching we face, especially in breast cancer, because there are so many therapies with some chance of working, but that chance decreases with each successive regimen, while [treatment] toxicity remains the same or increases," said Dr. Daniel Hayes, clinical director of the Breast Oncology Program at the University of Michigan Comprehensive Cancer Center in Ann Arbor.

Experts also say the decision must involve regular communication between doctor and patient through the course of the disease.

"It begins at the time of diagnosis and is very patient-specific," said Dr. R. Sean Morrison, professor of palliative medicine at the Mount Sinai School of Medicine in New York. "We want to understand what are their values and goals and what are values of treatment."

He also said that doctors need to find out whether it's a patient's wish to live as long as possible no matter what, or to live a better quality of life without the side effects of chemotherapy.

"If somebody wants to live as long as possible, I cam going to continue to recommend treatment until there's absolutely no benefit for them," said Morrison. "If it's important to not spend time in hospitals, I may make entirely different treatment decisions."

Cancer specialists say it's a discussion that many doctors unfortunately don't have with their patients.

"The patient will continue getting treatment despite potentially horrific side effects that interfere with her quality of life, and the oncologist continues to administer the chemotherapy, not wanting the patient to feel that he/she is giving up on her," said Lillie Shockney, an associate professor at the Johns Hopkins University School of Nursing in Baltimore.

"Doctors need to be educated that we have many other treatments besides chemotherapy," said Morrison. "Accompanying patients through a difficult illness, not abandoning them, and being there to listen to them is as important, if not more so, than prescribing one particular medication."

Research has shown that end-of-life care can actually help prolong life.

"It is an unfortunate myth that keeps being perpetuated that opting for palliative care shortens life," said Morrison. "When patients are comfortable, when the stress of pain is relieved, when their depression is treated, and their loved ones are supported, they actually live longer."

Final Days Full of Comfort and Love

In her remaining days, Edwards will benefit from the outpouring of support from the public as well as from having her loved ones around her.

"The doctors and nurses and caregivers are all gathered around and will provide the maximum amount of physical and psychological support that can be provided," said Ellis. "The dying process is different for every patient, but no one should have to die alone."

Ellis also said Edwards' family and friends will take tremendous comfort in being with her at this time.

"There is such a thing as a peaceful death, and the patient can reach closure with her loved ones."

ABC News' Emily Friedman, Jessica Hopper and Claire Shipman contributed to this report.

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#1. To: All (#0)

Hoping she goes into remission and lives a full and happy life.

Cancer takes too many of us.

-----------------------------------------------------------
Barrack Hussein Obama
President of the United States of America said that some Americans ; "They can come for the ride, but they gotta sit in back."

WhiteSands  posted on  2010-12-07   14:31:00 ET  Reply   Trace   Private Reply  


#2. To: WhiteSands (#1)

Hoping she goes into remission and lives a full and happy life.

Cancer takes too many of us.

Same view here.

Obama's first all-by-his-lonesome budget, btw, calls for a $1.17 trillion deficit.

Badeye  posted on  2010-12-07   14:33:28 ET  Reply   Trace   Private Reply  


#3. To: WhiteSands (#0)

who cares?

nobody.

Long live the Taliban Freedom Fighters!

continental op  posted on  2010-12-07   14:53:02 ET  Reply   Trace   Private Reply  


#4. To: WhiteSands (#0)

you've been posting these stupid tabloid articles for years, you lobotomized retard.

high time someone put you out of our misery.

Long live the Taliban Freedom Fighters!

continental op  posted on  2010-12-07   14:55:05 ET  Reply   Trace   Private Reply  


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